@article {298,
	title = {Mutation and evolutionary rates in adelie penguins from the antarctic},
	journal = {Plos Genetics},
	volume = {4},
	year = {2008},
	note = {id: 1195; Millar, Craig D Dodd, Andrew Anderson, Jennifer Gibb, Gillian C Ritchie, Peter A Baroni, Carlo Woodhams, Michael D Hendy, Michael D Lambert, David M PLoS Genet. 2008 Oct 3;4(10):e1000209.2546446},
	pages = {e1000209},
	abstract = {Precise estimations of molecular rates are fundamental to our understanding of the processes of evolution. In principle, mutation and evolutionary rates for neutral regions of the same species are expected to be equal. However, a number of recent studies have shown that mutation rates estimated from pedigree material are much faster than evolutionary rates measured over longer time periods. To resolve this apparent contradiction, we have examined the hypervariable region (HVR I) of the mitochondrial genome using families of Adelie penguins (Pygoscelis adeliae) from the Antarctic. We sequenced 344 bps of the HVR I from penguins comprising 508 families with 915 chicks, together with both their parents. All of the 62 germline heteroplasmies that we detected in mothers were also detected in their offspring, consistent with maternal inheritance. These data give an estimated mutation rate (micro) of 0.55 mutations/site/Myrs (HPD 95\% confidence interval of 0.29-0.88 mutations/site/Myrs) after accounting for the persistence of these heteroplasmies and the sensitivity of current detection methods. In comparison, the rate of evolution (k) of the same HVR I region, determined using DNA sequences from 162 known age sub-fossil bones spanning a 37,000-year period, was 0.86 substitutions/site/Myrs (HPD 95\% confidence interval of 0.53 and 1.17). Importantly, the latter rate is not statistically different from our estimate of the mutation rate. These results are in contrast to the view that molecular rates are time dependent.},
	issn = {1553-7404 (Electronic) 1553-7390 (Linking)},
	doi = {10.1371/journal.pgen.1000209},
	author = {Millar, C. D. and Dodd, A. and Anderson, J. and Gibb, G. C. and Ritchie, P. A. and Baroni, C. and Woodhams, M. D. and Hendy, M. D. and Lambert, D. M.}
}
@article {704,
	title = {Rates of evolution in ancient DNA from Adelie penguins},
	journal = {Science},
	volume = {295},
	year = {2002},
	note = {Lambert, D MRitchie, P AMillar, C DHolland, BDrummond, A JBaroni, CengResearch Support, Non-U.S. Gov{\textquoteright}tResearch Support, U.S. Gov{\textquoteright}t, P.H.S.2002/03/23 10:00Science. 2002 Mar 22;295(5563):2270-3.},
	month = {Mar 22},
	pages = {2270-3},
	abstract = {Well-preserved subfossil bones of Adelie penguins, Pygoscelis adeliae, underlie existing and abandoned nesting colonies in Antarctica. These bones, dating back to more than 7000 years before the present, harbor some of the best-preserved ancient DNA yet discovered. From 96 radiocarbon-aged bones, we report large numbers of mitochondrial haplotypes, some of which appear to be extinct, given the 380 living birds sampled. We demonstrate DNA sequence evolution through time and estimate the rate of evolution of the hypervariable region I using a Markov chain Monte Carlo integration and a least-squares regression analysis. Our calculated rates of evolution are approximately two to seven times higher than previous indirect phylogenetic estimates.},
	issn = {0036-8075 (Linking)},
	doi = {10.1126/science.1068105},
	author = {Lambert, D. M. and Ritchie, P. A. and Millar, C. D. and Holland, B. and Drummond, A. J. and Baroni, C.}
}
